As only limited data are available, Symbicort is not recommended for children younger than 6 years.
Administration of Symbicort to women who are breast-feeding should only be considered if the expected benefit to the mother is greater than any possible risk to the child. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. Many of these side effects can be managed, and some may go away on their own over time. In each secondary package there is 1 inhaler containing 30 doses or there are 1, 2, 3, 10 or 18 inhaler s containing 60 or 120 doses.
The excipient lactose contains small amounts of milk proteins, which may cause allergic reactions. There is some evidence of an increased risk of pneumonia with increasing steroid dose but this has not been demonstrated conclusively across all studies. Budesonide Budesonide is a glucocorticosteroid which when inhaled has a dose-dependent anti-inflammatory action in the airways, resulting in reduced symptoms and fewer asthma exacerbations.
Some patients may require up to a maximum of 4 inhalations twice daily.
Talk to a nurse. After you have primed the inhaler for the first time, the counter will read either 120 or 60, depending on which size was provided to you. For the full list of excipients, see section 6. Pregnancy For Symbicort or the concomitant treatment with formoterol and budesonide, no clinical data on exposed pregnancies are available.
Special patient groups: Severe exacerbations a. You may report side effects related to AstraZeneca products by clicking here. Budesonide is eliminated via metabolism mainly catalysed by the enzyme CYP3A4. Respiratory, thoracic and mediastinal disorders.
When ketoconazole was administered 12 hours after budesonide the concentration was on average increased only three-fold showing that separation of the administration times can reduce the increase in plasma levels. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Once asthma symptoms are controlled, consideration may be given to gradually reducing the dose of Symbicort.